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Targeted deletion of mouse Rad1 leads to deficient cellular DNA damage responses
The Rad1 gene is evolutionarily conserved from yeast to human. The fission yeast Schizosaccharomyces pombe Rad1 ortholog promotes cell survival against DNA damage and is required for G(2)/M checkpoint activation. In this study, mouse embryonic stem (ES) cells with a targeted deletion of Mrad1, the m...
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| 發表在: | Protein Cell |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Higher Education Press
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875338/ https://ncbi.nlm.nih.gov/pubmed/21637962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1049-7 |
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