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APP and APLP1 are degraded through autophagy in response to proteasome inhibition in neuronal cells
Amyloid beta (Aβ) precursor protein (APP) is a key protein in the pathogenesis of Alzheimer’s disease (AD). Both APP and its paralogue APLP1 (amyloid beta precursor-like protein 1) have multiple functions in cell adhesion and proliferation. Previously it was thought that autophagy is a novel beta-am...
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| Publicado no: | Protein Cell |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Higher Education Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875337/ https://ncbi.nlm.nih.gov/pubmed/21626267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1047-9 |
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