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Suppression of GSK3β by ERK mediates lipopolysaccharide induced cell migration in macrophage through β-catenin signaling

We investigate the role of β-catenin signaling in the response of macrophage to lipopolysaccharide (LPS) using RAW264.7 cells. LPS rapidly stimulated cytosolic β-catenin accumulation. β-catenin-mediated transcription was showed to be required for LPS induced gene expression and cell migration. Mecha...

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Pubblicato in:Protein Cell
Autori principali: Gong, Kai, Zhou, Fangfang, Huang, Huizhe, Gong, Yandao, Zhang, Long
Natura: Artigo
Lingua:Inglês
Pubblicazione: Higher Education Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875346/
https://ncbi.nlm.nih.gov/pubmed/22983902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-012-2058-x
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