New nsp8 isoform suggests mechanism for tuning viral RNA synthesis

During severe acute respiratory syndrome coronavirus (SARS-CoV) infection, the activity of the replication/transcription complexes (RTC) quickly peaks at 6 hours post infection (h.p.i) and then diminishes significantly in the late post-infection stages. This “down-up-down” regulation of RNA synthesi...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Li, Shuang, Zhao, Qi, Zhang, Yinjie, Zhang, Yang, Bartlam, Mark, Li, Xuemei, Rao, Zihe
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875168/
https://ncbi.nlm.nih.gov/pubmed/21203988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0028-8
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