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A dimeric structure of PD-L1: functional units or evolutionary relics?

PD-L1 is a member of the B7 protein family, most of whose members so far were identified as dimers in a solution and crystalline state, either complexed or uncomplexed with their ligand(s). The binding of PD-L1 with its receptor PD-1 (CD279) delivers an inhibitory signal regulating the T cell functi...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Chen, Yong, Liu, Peipei, Gao, Feng, Cheng, Hao, Qi, Jianxun, Gao, George F.
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875164/
https://ncbi.nlm.nih.gov/pubmed/21203985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0022-1
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