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A dimeric structure of PD-L1: functional units or evolutionary relics?
PD-L1 is a member of the B7 protein family, most of whose members so far were identified as dimers in a solution and crystalline state, either complexed or uncomplexed with their ligand(s). The binding of PD-L1 with its receptor PD-1 (CD279) delivers an inhibitory signal regulating the T cell functi...
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Publicado no: | Protein Cell |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Higher Education Press
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875164/ https://ncbi.nlm.nih.gov/pubmed/21203985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0022-1 |
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