Optical Imaging of Drug-Induced Metabolism Changes in Murine and Human Pancreatic Cancer Organoids Reveals Heterogeneous Drug Response

OBJECTIVES: Three-dimensional organoids derived from primary pancreatic ductal adenocarcinomas are an attractive platform for testing potential anticancer drugs on patient-specific tissue. Optical metabolic imaging (OMI) is a novel tool used to assess drug-induced changes in cellular metabolism, and...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Pancreas
Main Authors: Walsh, Alex J., Castellanos, Jason A., Nagathihalli, Nagaraj S., Merchant, Nipun B., Skala, Melissa C.
Format: Artigo
Jezik:Inglês
Izdano: Lippincott Williams & Wilkins 2016
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874911/
https://ncbi.nlm.nih.gov/pubmed/26495796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000000543
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