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Quantitative optical imaging of primary tumor organoid metabolism predicts drug response in breast cancer

There is a need for technologies to predict the efficacy of cancer treatment in individual patients. Here we show that optical metabolic imaging of organoids derived from primary tumors can predict therapeutic response of xenografts and measure anti-tumor drug responses in human-tumor derived organo...

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Main Authors: Walsh, Alex J., Cook, Rebecca S., Sanders, Melinda E., Aurisicchio, Luigi, Ciliberto, Gennaro, Arteaga, Carlos L., Skala, Melissa C.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167558/
https://ncbi.nlm.nih.gov/pubmed/25100563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0663
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