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Synthesis of 2-Aryl and 2-Vinylpyrrolidines via Copper-catalyzed Coupling of Styrenes and Dienes with Potassium β-Aminoethyltrifluoroborates

2-Arylpyrrolidines occur frequently in bioactive compounds and thus methods to access them from readily available reagents are valuable. We report a copper-catalyzed intermolecular carboamination of vinylarenes with potassium N-carbamoyl-β-aminoethyltrifluoroborates. The reaction occurs with termina...

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Publicat a:Org Lett
Autors principals: Um, Chanchamnan, Chemler, Sherry R.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874882/
https://ncbi.nlm.nih.gov/pubmed/27160334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b01259
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