Carboxylesterase 2 Prevents Liver Steatosis by Modulating Lipolysis, ER stress and Lipogenesis and Is Regulated by HNF4α

Non-alcoholic fatty liver disease (NAFLD) is a common liver disease that ranges from simple steatosis to non-alcoholic steatohepatitis (NASH). So far, the underlying mechanism remains poorly understood. Here we show that hepatic carboxylesterase 2 (CES2) is markedly reduced in NASH patients, diabeti...

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Bibliografske podrobnosti
izdano v:Hepatology
Main Authors: Li, Yuanyuan, Zalzala, Munaf, Jadhav, Kavita, Xu, Yang, Kasumov, Takhar, Yin, Liya, Zhang, Yanqiao
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874867/
https://ncbi.nlm.nih.gov/pubmed/26806650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28472
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