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Carboxylesterase 2 Prevents Liver Steatosis by Modulating Lipolysis, ER stress and Lipogenesis and Is Regulated by HNF4α
Non-alcoholic fatty liver disease (NAFLD) is a common liver disease that ranges from simple steatosis to non-alcoholic steatohepatitis (NASH). So far, the underlying mechanism remains poorly understood. Here we show that hepatic carboxylesterase 2 (CES2) is markedly reduced in NASH patients, diabeti...
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| Publié dans: | Hepatology |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4874867/ https://ncbi.nlm.nih.gov/pubmed/26806650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28472 |
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