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Zinc Finger Domain of the PRDM9 Gene on Chromosome 1 Exhibits High Diversity in Ruminants but Its Paralog PRDM7 Contains Multiple Disruptive Mutations

PRDM9 is the sole hybrid sterility gene identified so far in vertebrates. PRDM9 gene encodes a protein with an immensely variable zinc-finger (ZF) domain that determines the site of meiotic recombination hotspots genome-wide. In this study, the terminal ZF domain of PRDM9 on bovine chromosome 1 and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ahlawat, Sonika, Sharma, Priyanka, Sharma, Rekha, Arora, Reena, De, Sachinandan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874674/
https://ncbi.nlm.nih.gov/pubmed/27203728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156159
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