Chargement en cours...
Dexamethasone treatment promotes Bcl-2-dependence in multiple myeloma resulting in sensitivity to Venetoclax
Venetoclax (ABT-199), a specific inhibitor of the anti-apoptotic protein Bcl-2, is currently in phase I clinical trials for multiple myeloma. Results suggest that venetoclax is only active in a small cohort of patients therefore we wanted to determine its efficacy when used in combination. Combining...
Enregistré dans:
| Publié dans: | Leukemia |
|---|---|
| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4874660/ https://ncbi.nlm.nih.gov/pubmed/26707935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.350 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|