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Time-resolved functional analysis of acute impairment of frataxin expression in an inducible cell model of Friedreich ataxia
Friedreich ataxia is a neurodegenerative disease caused by a GAA triplet repeat expansion in the first intron of the frataxin gene, which results in reduced expression levels of the corresponding protein. Despite numerous animal and cellular models, therapeutic options that mechanistically address i...
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| Publié dans: | Biol Open |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Company of Biologists Ltd
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4874353/ https://ncbi.nlm.nih.gov/pubmed/27106929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.017004 |
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