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Time-resolved functional analysis of acute impairment of frataxin expression in an inducible cell model of Friedreich ataxia
Friedreich ataxia is a neurodegenerative disease caused by a GAA triplet repeat expansion in the first intron of the frataxin gene, which results in reduced expression levels of the corresponding protein. Despite numerous animal and cellular models, therapeutic options that mechanistically address i...
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| 出版年: | Biol Open |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Company of Biologists Ltd
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4874353/ https://ncbi.nlm.nih.gov/pubmed/27106929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.017004 |
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