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Constitutive activation of Pim1 kinase is a therapeutic target for adult T-cell leukemia

Human T-cell leukemia virus type 1 (HTLV-1)–associated adult T-cell leukemia and T-cell lymphoma (ATL) are aggressive diseases with poor prognoses, limited therapeutic options, and no curative treatment. In this study, we used a mouse model of ATL and restored expression of the microRNA, miR-124a, t...

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Foilsithe in:Blood
Main Authors: Bellon, Marcia, Lu, Ling, Nicot, Christophe
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874225/
https://ncbi.nlm.nih.gov/pubmed/26813676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-11-685032
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