Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells

Aberrant immune responses represent the underlying cause of central nervous system (CNS) autoimmunity, including multiple sclerosis (MS). Recent evidence implicated the crosstalk between coagulation and immunity in CNS autoimmunity. Here we identify coagulation factor XII (FXII), the initiator of th...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Göbel, Kerstin, Pankratz, Susann, Asaridou, Chloi-Magdalini, Herrmann, Alexander M., Bittner, Stefan, Merker, Monika, Ruck, Tobias, Glumm, Sarah, Langhauser, Friederike, Kraft, Peter, Krug, Thorsten F., Breuer, Johanna, Herold, Martin, Gross, Catharina C., Beckmann, Denise, Korb-Pap, Adelheid, Schuhmann, Michael K., Kuerten, Stefanie, Mitroulis, Ioannis, Ruppert, Clemens, Nolte, Marc W., Panousis, Con, Klotz, Luisa, Kehrel, Beate, Korn, Thomas, Langer, Harald F., Pap, Thomas, Nieswandt, Bernhard, Wiendl, Heinz, Chavakis, Triantafyllos, Kleinschnitz, Christoph, Meuth, Sven G.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873982/
https://ncbi.nlm.nih.gov/pubmed/27188843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11626
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires