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Bridging the gap: heparan sulfate and Scube2 assemble Sonic hedgehog release complexes at the surface of producing cells

Decision making in cellular ensembles requires the dynamic release of signaling molecules from the producing cells into the extracellular compartment. One important example of molecules that require regulated release in order to signal over several cell diameters is the Hedgehog (Hh) family, because...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Jakobs, P., Schulz, P., Ortmann, C., Schürmann, S., Exner, S., Rebollido-Rios, R., Dreier, R., Seidler, D. G., Grobe, K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873810/
https://ncbi.nlm.nih.gov/pubmed/27199253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26435
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