Fast MS/MS acquisition without dynamic exclusion enables precise and accurate quantification of proteome by MS/MS fragment intensity

Most currently proteomic studies use data-dependent acquisition with dynamic exclusion to identify and quantify the peptides generated by the digestion of biological sample. Although dynamic exclusion permits more identifications and higher possibility to find low abundant proteins, stochastic and i...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Zhang, Shen, Wu, Qi, Shan, Yichu, Zhao, Qun, Zhao, Baofeng, Weng, Yejing, Sui, Zhigang, Zhang, Lihua, Zhang, Yukui
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873735/
https://ncbi.nlm.nih.gov/pubmed/27198003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26392
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