Nano LC-MS using capillary columns enables accurate quantification of modified ribonucleosides at low femtomol levels

Post-transcriptional chemical modifications of (t)RNA molecules are crucial in fundamental biological processes, such as translation. Despite their biological importance and accumulating evidence linking them to various human diseases, technical challenges have limited their detection and accurate q...

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Gepubliceerd in:RNA
Hoofdauteurs: Sarin, L. Peter, Kienast, Sandra D., Leufken, Johannes, Ross, Robert L., Dziergowska, Agnieszka, Debiec, Katarzyna, Sochacka, Elzbieta, Limbach, Patrick A., Fufezan, Christian, Drexler, Hannes C.A., Leidel, Sebastian A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140458/
https://ncbi.nlm.nih.gov/pubmed/30012570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.065482.117
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