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An evolutionary approach uncovers a diverse response of tRNA 2-thiolation to elevated temperatures in yeast

Chemical modifications of transfer RNA (tRNA) molecules are evolutionarily well conserved and critical for translation and tRNA structure. Little is known how these nucleoside modifications respond to physiological stress. Using mass spectrometry and complementary methods, we defined tRNA modificati...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Alings, Fiona, Sarin, L. Peter, Fufezan, Christian, Drexler, Hannes C.A., Leidel, Sebastian A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338348/
https://ncbi.nlm.nih.gov/pubmed/25505025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.048199.114
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