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An evolutionary approach uncovers a diverse response of tRNA 2-thiolation to elevated temperatures in yeast

Chemical modifications of transfer RNA (tRNA) molecules are evolutionarily well conserved and critical for translation and tRNA structure. Little is known how these nucleoside modifications respond to physiological stress. Using mass spectrometry and complementary methods, we defined tRNA modificati...

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Bibliografske podrobnosti
izdano v:RNA
Main Authors: Alings, Fiona, Sarin, L. Peter, Fufezan, Christian, Drexler, Hannes C.A., Leidel, Sebastian A.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338348/
https://ncbi.nlm.nih.gov/pubmed/25505025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.048199.114
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