Fast MS/MS acquisition without dynamic exclusion enables precise and accurate quantification of proteome by MS/MS fragment intensity

Most currently proteomic studies use data-dependent acquisition with dynamic exclusion to identify and quantify the peptides generated by the digestion of biological sample. Although dynamic exclusion permits more identifications and higher possibility to find low abundant proteins, stochastic and i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Shen, Wu, Qi, Shan, Yichu, Zhao, Qun, Zhao, Baofeng, Weng, Yejing, Sui, Zhigang, Zhang, Lihua, Zhang, Yukui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873735/
https://ncbi.nlm.nih.gov/pubmed/27198003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26392
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