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Dietary salt regulates uroguanylin expression and signaling activity in the kidney, but not in the intestine

The peptide uroguanylin (Ugn) is expressed at significant levels only in intestine and kidney, and is stored in both tissues primarily (perhaps exclusively) as intact prouroguanylin (proUgn). Intravascular infusion of either Ugn or proUgn evokes well‐characterized natriuretic responses in rodents. F...

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Bibliografske podrobnosti
izdano v:Physiol Rep
Main Authors: Fellner, Robert C., Moss, Nicholas G., Goy, Michael F.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873633/
https://ncbi.nlm.nih.gov/pubmed/27185905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12782
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