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Circulating Prouroguanylin Is Processed to Its Active Natriuretic Form Exclusively within the Renal Tubules

The intestine and kidney are linked by a mechanism that increases salt excretion in response to salt intake. The peptide uroguanylin (UGn) is thought to mediate this signaling axis. Therefore, it was surprising to find (as reported in a companion publication) that UGn is stored in the intestine and...

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Detalhes bibliográficos
Main Authors: Qian, Xun, Moss, Nicholas G., Fellner, Robert C., Goy, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553375/
https://ncbi.nlm.nih.gov/pubmed/18499761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1724
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