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Toxicogenomic assessment of liver responses following subchronic exposure to furan in Fischer F344 rats
Furan is a widely used industrial chemical and a contaminant in heated foods. Chronic furan exposure causes cholangiocarcinoma and hepatocellular tumors in rats at doses of 2 mg/kg bw/day or greater, with gender differences in frequency and severity. The hepatic transcriptional alterations induced b...
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| Publicado no: | Arch Toxicol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4873526/ https://ncbi.nlm.nih.gov/pubmed/26194646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-015-1561-2 |
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