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Subchronic exposure to phytoestrogens alone and in combination with diethylstilbestrol - pituitary tumor induction in Fischer 344 rats

BACKGROUND: Subchronic administration of the potent pharmaceutical estrogen diethylstilbestrol (DES) to female Fischer 344 (F344) rats induces growth of large, hemorrhagic pituitaries that progress to tumors. Phytoestrogens (dietary plant estrogens) are hypothesized to be potential tumor inhibitors...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Jeng, Yow-Jiun, Kochukov, Mikhail, Nauduri, Dhananjaya, Kaphalia, Bhupendra S, Watson, Cheryl S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881934/
https://ncbi.nlm.nih.gov/pubmed/20459739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-7075-7-40
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