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Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment
There is increasing interest in the use of quantitative transcriptomic data to determine benchmark dose (BMD) and estimate a point of departure (POD) for human health risk assessment. Although studies have shown that transcriptional PODs correlate with those derived from apical endpoint changes, the...
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| Publicat a: | Arch Toxicol |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Berlin Heidelberg
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5399047/ https://ncbi.nlm.nih.gov/pubmed/27928627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1886-5 |
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