Cyclin E associates with the lipogenic enzyme ATP-citrate lyase to enable malignant growth of breast cancer cells

Cyclin E (CCNE) is altered in nearly a third of invasive breast cancers where it is a powerful independent predictor of survival in women with stage I-III disease. Full-length cyclin E is post-translationally cleaved into low molecular weight (LMW-E) isoforms, which are tumor-specific and accumulate...

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Pubblicato in:Cancer Res
Autori principali: Lucenay, Kimberly S., Doostan, Iman, Karakas, Cansu, Bui, Tuyen, Ding, Zhiyong, Mills, Gordon B., Hunt, Kelly K, Keyomarsi, Khandan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873469/
https://ncbi.nlm.nih.gov/pubmed/26928812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1646
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