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Deletion of interstitial genes between TMPRSS2 and ERG promotes prostate cancer progression

TMPRSS2-ERG gene fusions that occur frequently in human prostate cancers can be generated either through insertional chromosomal rearrangement or by intrachromosomal deletion. Genetically, a key difference between these two mechanisms is that the latter results in deletion of a ~3Mb interstitial reg...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Linn, Douglas E., Penney, Kathryn L., Bronson, Roderick T., Mucci, Lorelei A., Li, Zhe
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873435/
https://ncbi.nlm.nih.gov/pubmed/26880803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1911
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