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MR Studies of Glioblastoma Models Treated with Dual PI3K/mTOR Inhibitor and Temozolomide – Metabolic Changes are Associated with Enhanced Survival
Current standard of care for glioblastoma (GBM) is surgical resection, radiation, and treatment with Temozolomide (TMZ). However, resistance to current therapies and recurrence are common. To improve survival, agents that target the phosphoinositide-3-kinase (PI3K) signaling pathway, which is activa...
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| Publicado no: | Mol Cancer Ther |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4873419/ https://ncbi.nlm.nih.gov/pubmed/26883274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0769 |
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