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SM-TF: a structural database of small molecule-transcription factor complexes

Transcription factors (TFs) are the proteins involved in the transcription process, ensuring the correct expression of specific genes. Numerous diseases arise from the dysfunction of specific TFs. In fact, over 30 TFs have been identified as therapeutic targets of about 9% of the approved drugs. In...

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Bibliografiska uppgifter
I publikationen:J Comput Chem
Huvudupphovsmän: Xu, Xianjin, Ma, Zhiwei, Sun, Hongmin, Zou, Xiaoqin
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873394/
https://ncbi.nlm.nih.gov/pubmed/27010673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.24370
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