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A complex task? Direct modulation of transcription factors with small molecules
Transcription factors with aberrant activity in disease are promising yet untested targets for therapeutic development, particularly in oncology. Directly inhibiting or activating the function of a transcription factor requires specific disruption or recruitment of protein-protein or protein-DNA int...
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| 第一著者: | |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3248789/ https://ncbi.nlm.nih.gov/pubmed/20395165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2010.03.022 |
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