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SM-TF: a structural database of small molecule-transcription factor complexes

Transcription factors (TFs) are the proteins involved in the transcription process, ensuring the correct expression of specific genes. Numerous diseases arise from the dysfunction of specific TFs. In fact, over 30 TFs have been identified as therapeutic targets of about 9% of the approved drugs. In...

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Detalhes bibliográficos
Publicado no:J Comput Chem
Main Authors: Xu, Xianjin, Ma, Zhiwei, Sun, Hongmin, Zou, Xiaoqin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873394/
https://ncbi.nlm.nih.gov/pubmed/27010673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.24370
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