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Mutant p53 promotes epithelial ovarian cancer by regulating tumor differentiation, metastasis, and responsiveness to steroid hormones

Mutations in the tumor protein p53 (TP53) are the most frequently occurring genetic events in high-grade ovarian cancers, especially the prevalence of the TP53R175H mutant allele. In this study, we investigated the impact of the TP53R175H mutant allele on epithelial ovarian cancer (EOC) in vivo. We...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancer Res
Päätekijät: Ren, Yi A, Mullany, Lisa K, Liu, Zhilin, Herron, Alan J, Wong, Kwong-Kwok, Richards, JoAnne S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873372/
https://ncbi.nlm.nih.gov/pubmed/26964623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1046
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