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Tumor Repressor Protein 53 and Steroid Hormones Provide a New Paradigm for Ovarian Cancer Metastases

The functional status of the tumor repressor protein (TP53 or TRP53) is a defining feature of ovarian cancer. Mutant or null alleles of TP53 are expressed in greater than 90% of all high-grade serous adenocarcinomas. Wild-type TP53 is elevated in low-grade serous adenocarcinomas in women and in our...

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Hlavní autoři: Mullany, Lisa K., Liu, Zhilin, Wong, Kwong-Kwok, Deneke, Victoria, Ren, Yi Athena, Herron, Alan, Richards, JoAnne S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874458/
https://ncbi.nlm.nih.gov/pubmed/24264574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1308
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