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Tumor Repressor Protein 53 and Steroid Hormones Provide a New Paradigm for Ovarian Cancer Metastases
The functional status of the tumor repressor protein (TP53 or TRP53) is a defining feature of ovarian cancer. Mutant or null alleles of TP53 are expressed in greater than 90% of all high-grade serous adenocarcinomas. Wild-type TP53 is elevated in low-grade serous adenocarcinomas in women and in our...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Endocrine Society
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3874458/ https://ncbi.nlm.nih.gov/pubmed/24264574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1308 |
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