Nutlin-3a: A Potential Therapeutic Opportunity for TP53 Wild-Type Ovarian Carcinomas

Epithelial ovarian cancer is a diverse molecular and clinical disease, yet standard treatment is the same for all subtypes. TP53 mutations represent a node of divergence in epithelial ovarian cancer histologic subtypes and may represent a therapeutic opportunity in subtypes expressing wild type, inc...

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Foilsithe in:PLoS One
Main Authors: Crane, Erin K., Kwan, Suet-Yan, Izaguirre, Daisy I., Tsang, Yvonne T. M., Mullany, Lisa K., Zu, Zhifei, Richards, JoAnne S., Gershenson, David M., Wong, Kwong-Kwok
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527847/
https://ncbi.nlm.nih.gov/pubmed/26248031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135101
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