Wild-Type Tumor Repressor Protein 53 (TRP53) Promotes Ovarian Cancer Cell Survival

Loss of Pten in the Kras(G12D);Amhr2-Cre mutant mice leads to the transformation of ovarian surface epithelial (OSE) cells and rapid development of low-grade, invasive serous adenocarcinomas. Tumors occur with 100% penetrance and express elevated levels of wild-type tumor repressor protein 53 (TRP53...

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Detaylı Bibliyografya
Asıl Yazarlar: Mullany, Lisa K., Liu, Zhilin, King, Erin R., Wong, Kwong-Kwok, Richards, JoAnne S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2012
Konular:
Cancer-Oncogenes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320246/
https://ncbi.nlm.nih.gov/pubmed/22396451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-2131
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