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A calpain-2 selective inhibitor enhances learning & memory by prolonging ERK activation

While calpain-1 activation is required for LTP induction by theta burst stimulation (TBS), calpain-2 activation limits its magnitude during the consolidation period. A selective calpain-2 inhibitor applied either before or shortly after TBS enhanced the degree of potentiation. In the present study,...

詳細記述

保存先:
書誌詳細
出版年:Neuropharmacology
主要な著者: Liu, Yan, Wang, Yubin, Zhu, Guoqi, Sun, Jiandong, Bi, Xiaoning, Baudry, Michel
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873344/
https://ncbi.nlm.nih.gov/pubmed/26907807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.02.022
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