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Calpain-1 deletion impairs mGluR-dependent LTD and fear memory extinction

Recent studies indicate that calpain-1 is required for the induction of long-term potentiation (LTP) elicited by theta-burst stimulation in field CA1 of hippocampus. Here we determined the contribution of calpain-1 in another type of synaptic plasticity, the long-term depression (LTD) elicited by ac...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhu, Guoqi, Briz, Victor, Seinfeld, Jeff, Liu, Yan, Bi, Xiaoning, Baudry, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311935/
https://ncbi.nlm.nih.gov/pubmed/28202907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42788
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