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A calpain-2 selective inhibitor enhances learning & memory by prolonging ERK activation
While calpain-1 activation is required for LTP induction by theta burst stimulation (TBS), calpain-2 activation limits its magnitude during the consolidation period. A selective calpain-2 inhibitor applied either before or shortly after TBS enhanced the degree of potentiation. In the present study,...
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| Publicado no: | Neuropharmacology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4873344/ https://ncbi.nlm.nih.gov/pubmed/26907807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.02.022 |
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