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Assessing histidine tags for recruiting deoxyribozymes to catalyze peptide and protein modification reactions()

We evaluate the ability of hexahistidine (His(6)) tags on peptide and protein substrates to recruit deoxyribozymes for modifying those substrates. For two different deoxyribozymes, one that creates tyrosine-RNA nucleopeptides and another that phosphorylates tyrosine side chains, we find substantial...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Chu, Chih-Chi, Silverman, Scott K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872867/
https://ncbi.nlm.nih.gov/pubmed/27138704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob00716c
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