Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells

Although hypoxia is a prominent feature contributing to the therapeutic resistance of hepatocellular carcinoma cells (HCC) against chemotherapeutic agents, including the Topoisomerase I inhibitor SN38, the underlying mechanism is not fully understood and its understanding remains a major clinical ch...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dai, Xiao-Yang, Zhuang, Lin-Han, Wang, Dan-Dan, Zhou, Tian-Yi, Chang, Lin-Lin, Gai, Ren-Hua, Zhu, Di-Feng, Yang, Bo, Zhu, Hong, He, Qiao-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872759/
https://ncbi.nlm.nih.gov/pubmed/26771844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6903
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