Presence of sst5TMD4, a truncated splice variant of the somatostatin receptor subtype 5, is associated to features of increased aggressiveness in pancreatic neuroendocrine tumors

PURPOSE: Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are rare and heterogeneous tumors, and their biological behavior is not well known. We studied the presence and potential functional roles of somatostatin receptors (sst1-5), focusing particularly on the truncated variants (sst5TMD4, s...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sampedro-Núñez, Miguel, Luque, Raúl M., Ramos-Levi, Ana M., Gahete, Manuel D., Serrano-Somavilla, Ana, Villa-Osaba, Alicia, Adrados, Magdalena, Ibáñez-Costa, Alejandro, Martín-Pérez, Elena, Culler, Michael D., Marazuela, Mónica, Castaño, Justo P.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872735/
https://ncbi.nlm.nih.gov/pubmed/26673010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6565
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