In1-ghrelin, a splice variant of ghrelin gene, is associated with the evolution and aggressiveness of human neuroendocrine tumors: Evidence from clinical, cellular and molecular parameters

Ghrelin system comprises a complex family of peptides, receptors (GHSRs), and modifying enzymes [e.g. ghrelin-O-acyl-transferase (GOAT)] that control multiple pathophysiological processes. Aberrant alternative splicing is an emerging cancer hallmark that generates altered proteins with tumorigenic c...

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發表在:Oncotarget
Main Authors: Luque, Raul M., Sampedro-Nuñez, Miguel, Gahete, Manuel D., Ramos-Levi, Ana, Ibáñez-Costa, Alejandro, Rivero-Cortés, Esther, Serrano-Somavilla, Ana, Adrados, Magdalena, Culler, Michael D., Castaño, Justo P., Marazuela, Mónica
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2015
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637309/
https://ncbi.nlm.nih.gov/pubmed/26124083
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