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NOX2 Activation of Natural Killer T Cells Is Blocked by the Adenosine A(2A) Receptor to Inhibit Lung Ischemia–Reperfusion Injury
Rationale: Ischemia–reperfusion (IR) injury after lung transplantation, which affects both short- and long-term allograft survival, involves activation of NADPH oxidase 2 (NOX2) and activation of invariant natural killer T (iNKT) cells to produce IL-17. Adenosine A(2A) receptor (A(2A)R) agonists are...
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| Pubblicato in: | Am J Respir Crit Care Med |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Thoracic Society
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872653/ https://ncbi.nlm.nih.gov/pubmed/26757359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201506-1253OC |
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