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Natural Killer T Cell–derived IL-17 Mediates Lung Ischemia–Reperfusion Injury

Rationale: We recently implicated a role for CD4(+) T cells and demonstrated elevated IL-17A expression in lung ischemia–reperfusion (IR) injury. However, identification of the specific subset of CD4(+) T cells and their mechanistic role in IR injury remains unknown. Objectives: We tested the hypoth...

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Detalhes bibliográficos
Main Authors: Sharma, Ashish K., LaPar, Damien J., Zhao, Yunge, Li, Li, Lau, Christine L., Kron, Irving L., Iwakura, Yoichiro, Okusa, Mark D., Laubach, Victor E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137143/
https://ncbi.nlm.nih.gov/pubmed/21317314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201007-1173OC
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