Transcriptional repression of p27 is essential for murine embryonic development

The Nczf gene has been identified as one of Ncx target genes and encodes a novel KRAB zinc-finger protein, which functions as a sequence specific transcriptional repressor. In order to elucidate Nczf functions, we generated Nczf knockout (Nczf−/−) mice. Nczf−/− mice died around embryonic day 8.5 (E8...

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Vydáno v:Sci Rep
Hlavní autoři: Teratake, Youichi, Kuga, Chisa, Hasegawa, Yuta, Sato, Yoshiharu, Kitahashi, Masayasu, Fujimura, Lisa, Watanabe-Takano, Haruko, Sakamoto, Akemi, Arima, Masafumi, Tokuhisa, Takeshi, Hatano, Masahiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872541/
https://ncbi.nlm.nih.gov/pubmed/27196371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26244
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