Polymyxin Resistance in Acinetobacter baumannii: Genetic Mutations and Transcriptomic Changes in Response to Clinically Relevant Dosage Regimens

Polymyxins are often last-line therapeutic agents used to treat infections caused by multidrug-resistant A. baumannii. Recent reports of polymyxin-resistant A. baumannii highlight the urgent need for research into mechanisms of polymyxin resistance. This study employed genomic and transcriptomic ana...

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Pubblicato in:Sci Rep
Autori principali: Cheah, Soon-Ee, Johnson, Matthew D., Zhu, Yan, Tsuji, Brian T., Forrest, Alan, Bulitta, Jurgen B., Boyce, John D., Nation, Roger L., Li, Jian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872528/
https://ncbi.nlm.nih.gov/pubmed/27195897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26233
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