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The functional serotonin 1a receptor promoter polymorphism, rs6295, is associated with psychiatric illness and differences in transcription

The G/C single-nucleotide polymorphism in the serotonin 1a receptor promoter, rs6295, has previously been linked with depression, suicide and antidepressant responsiveness. In vitro studies suggest that rs6295 may have functional effects on the expression of the serotonin 1a receptor gene (HTR1A) th...

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Vydáno v:Transl Psychiatry
Hlavní autoři: Donaldson, Z R, le Francois, B, Santos, T L, Almli, L M, Boldrini, M, Champagne, F A, Arango, V, Mann, J J, Stockmeier, C A, Galfalvy, H, Albert, P R, Ressler, K J, Hen, R
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872437/
https://ncbi.nlm.nih.gov/pubmed/26926882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2015.226
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