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The influence of the rs6295 gene polymorphism on serotonin-1A receptor distribution investigated with PET in patients with major depression applying machine learning

Major depressive disorder (MDD) is the most common neuropsychiatric disease and despite extensive research, its genetic substrate is still not sufficiently understood. The common polymorphism rs6295 of the serotonin-1A receptor gene (HTR1A) is affecting the transcriptional regulation of the 5-HT(1A)...

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Vydáno v:Transl Psychiatry
Hlavní autoři: Kautzky, A, James, G M, Philippe, C, Baldinger-Melich, P, Kraus, C, Kranz, G S, Vanicek, T, Gryglewski, G, Wadsak, W, Mitterhauser, M, Rujescu, D, Kasper, S, Lanzenberger, R
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537636/
https://ncbi.nlm.nih.gov/pubmed/28608854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2017.108
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