Functional Interrogation of a Depression-Related Serotonergic Single Nucleotide Polymorphism, rs6295, Using a Humanized Mouse Model

The serotonin 1A receptor (5-HT1A) system has been extensively implicated in modulating mood and behavior. Notably, 5-HT1A levels in humans display remarkable variation, and differences in receptor levels have been linked with a variety of psychiatric disorders. Further, reduction of receptor levels...

Full description

Saved in:
Bibliographic Details
Published in:ACS Chem Neurosci
Main Authors: Cunningham, Ashley M., Santos, Tabia L., Gutzeit, Vanessa A., Hamilton, Heather, Hen, René, Donaldson, Zoe R.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6878663/
https://ncbi.nlm.nih.gov/pubmed/30694044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00638
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items